Brain and Behavior (Apr 2021)

Magnetic resonance tractography exhibiting retrograde degeneration of the corticospinal tract in a patient with a unilateral spinal cord tumor

  • Yusuke Osaki,
  • Wataru Sako,
  • Masafumi Harada,
  • Yuishin Izumi

DOI
https://doi.org/10.1002/brb3.2020
Journal volume & issue
Vol. 11, no. 4
pp. n/a – n/a

Abstract

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Abstract Background Transection‐induced axonal retrograde degeneration, in contrast to Wallerian degeneration, has not been widely recognized in clinical practice. Aims of the Study To assess a potential of corticospinal tractography for detecting axonal retrograde degeneration. Methods We assessed the corticospinal tractography of a 74‐year‐old woman with monoplegia of the lower limb due to a unilateral thoracic spinal cord tumor. Results The tractography revealed integrity reduction of the corticospinal tract in the cerebra contralateral to the spinal cord tumor. Conclusions The present report supports that magnetic resonance tractography has the potential for detecting this under‐recognized phenomenon.

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