Acta Pediátrica de México (Jul 2014)
Retreatment with intravenous immunoglobulin (IVIG) of refractory Guillain Barre syndrome in children
Abstract
Guillain-Barré syndrome (GBS) is an acute symmetrical pa- ralyzing disease due to a demyelinating polyrradiculoneuropathy, often induced by a preceding infection 1. The main modalities for the treatment of GBS include plasmapheresis and intrave- nous immune globulin. Reports of the use of IVIG in children with GBS are limited: 1 g/kg for two days or 400 mg/kg for five days. While these studies in children are not definitive because of design limitations, their results are consistent with the larger randomized trials in adults 2,3.
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