PLoS ONE (Jan 2022)

Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience

  • Karthik Murugiah,
  • Lian Chen,
  • Rachel P. Dreyer,
  • Georgios Bouras,
  • Basmah Safdar,
  • Rohan Khera,
  • Yuan Lu,
  • Erica S. Spatz,
  • Vivian G. Ng,
  • Aakriti Gupta,
  • Héctor Bueno,
  • Marysia S. Tweet,
  • John A. Spertus,
  • Sharonne N. Hayes,
  • Alexandra Lansky,
  • Harlan M. Krumholz

Journal volume & issue
Vol. 17, no. 3

Abstract

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Background Data on health status outcomes after spontaneous coronary artery dissection (SCAD) are limited. Methods and findings Using the Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients (VIRGO) study we compared patients with SCAD and other acute myocardial infarction (AMI) at presentation (baseline), 1-month, and-12 months using standardized health status instruments. Among 3572 AMI patients ≤ 55 years, 67 had SCAD. SCAD patients were younger (median age (IQR) 45 (40.5–51) years vs. 48 (44–52) in other AMI, p = 0.003), more often female (92.5% vs. 66.6%), have college education (73.1% vs. 51.7%) and household income >$100,000 (43.3% vs. 17.7% (All pConclusions SCAD patients fare marginally better than other AMI patients on most health status instruments and have similar 12-month health status recovery. Better pre-event health status suggests a need to modify exercise prescriptions and cardiac rehabilitation protocols to better assist this physically active population to recover.