Journal of Ovarian Research (May 2025)

Gut microbiota and ovarian diseases: a new therapeutic perspective

  • Shan Ju,
  • Zhen Yang Kang,
  • Li Ya Yang,
  • Yong Jun Xia,
  • Yi Ming Guo,
  • Sui Li,
  • Hongli Yan,
  • Ming Kang Qi,
  • Hui Ping Wang,
  • Lian Zhong

DOI
https://doi.org/10.1186/s13048-025-01684-5
Journal volume & issue
Vol. 18, no. 1
pp. 1 – 17

Abstract

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Abstract The gut microbiota is a complex community of microorganisms that inhabit the human gastrointestinal tract, helping to maintain the ecological balance of the body’s internal and external environments. Disruptions in the composition and diversity of gut microbiota, as well as changes in their metabolic functions, can link to the development and severity of conditions such as premature ovarian insufficiency, polycystic ovary syndrome, and ovarian tumors. This article thoroughly reviews recent research on the connection between gut microbiota and ovarian diseases, providing fresh perspectives on their prevention, pathogenesis, and treatment.

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