mBio
(Feb 2021)
How Phagocytic Cells Kill Different Bacteria: a Quantitative Analysis Using Dictyostelium discoideum
Tania Jauslin,
Otmane Lamrabet,
Xenia Crespo-Yañez,
Anna Marchetti,
Imen Ayadi,
Estelle Ifrid,
Cyril Guilhen,
Matthias Leippe,
Pierre Cosson
Affiliations
Tania Jauslin
Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Otmane Lamrabet
ORCiD Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Xenia Crespo-Yañez
Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Anna Marchetti
Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Imen Ayadi
Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Estelle Ifrid
Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Cyril Guilhen
Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Matthias Leippe
Zoological Institute, Comparative Immunobiology, University of Kiel, Kiel, Germany
Pierre Cosson
ORCiD Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
DOI
https://doi.org/10.1128/mBio.03169-20
Journal volume & issue
Vol. 12,
no. 1
Abstract
Read online
Phagocytic cells ingest and kill bacteria, a process essential for the defense of the human body against infections. Many potential killing mechanisms have been identified in phagocytic cells, including free radicals, toxic ions, enzymes, and permeabilizing peptides.
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