How Phagocytic Cells Kill Different Bacteria: a Quantitative Analysis Using Dictyostelium discoideum

Tania Jauslin; Otmane Lamrabet; Xenia Crespo-Yañez; Anna Marchetti; Imen Ayadi; Estelle Ifrid; Cyril Guilhen; Matthias Leippe; Pierre Cosson

doi:10.1128/mBio.03169-20

mBio (Feb 2021)

How Phagocytic Cells Kill Different Bacteria: a Quantitative Analysis Using Dictyostelium discoideum

Tania Jauslin,
Otmane Lamrabet,
Xenia Crespo-Yañez,
Anna Marchetti,
Imen Ayadi,
Estelle Ifrid,
Cyril Guilhen,
Matthias Leippe,
Pierre Cosson

Affiliations

Tania Jauslin: Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Otmane Lamrabet: ORCiD; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Xenia Crespo-Yañez: Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Anna Marchetti: Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Imen Ayadi: Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Estelle Ifrid: Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Cyril Guilhen: Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Matthias Leippe: Zoological Institute, Comparative Immunobiology, University of Kiel, Kiel, Germany
Pierre Cosson: ORCiD; Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland

DOI: https://doi.org/10.1128/mBio.03169-20
Journal volume & issue: Vol. 12, no. 1

Abstract

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Phagocytic cells ingest and kill bacteria, a process essential for the defense of the human body against infections. Many potential killing mechanisms have been identified in phagocytic cells, including free radicals, toxic ions, enzymes, and permeabilizing peptides.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal