804 Genetic dissection of TLR9 reveals complex regulatory and cryptic pro-inflammatory roles in murine lupus

• Mark J Shlomchik,
• Claire Leibler,
• Shinu John,
• Shuchi Smita,
• Rachael Gordon,
• Sebastien Gingras,
• Sheldon Bastacky,
• Kensuke Miyake,
• Rebecca A Elsner,
• Kayla B Thomas,
• Stephen Joachim,
• Russell C Levack,
• Derrick Callahan,
• Ryutaro Fukui,
• Kevin M Nickerson

Affiliations

Mark J Shlomchik

University of Pittsburgh School of Medicine, Department of Immunology

Claire Leibler

1Department of Immunology

Shinu John

1Department of Immunology

Shuchi Smita

1Department of Immunology

Rachael Gordon

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Sebastien Gingras

1Department of Immunology

Sheldon Bastacky

3Department of Pathology, University of Pittsburgh, USA

Kensuke Miyake

Division of Innate Immunity, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

Rebecca A Elsner

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Kayla B Thomas

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Stephen Joachim

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Russell C Levack

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Derrick Callahan

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Ryutaro Fukui

5Division of Innate Immunity, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan

Kevin M Nickerson

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA