Медицинский совет (Dec 2013)
Polyneuropathy: modern aspects of metabolic therapy
Abstract
The article is a literature review on the treatment of metabolic polyneuropathy in patients with diabetes mellitus type 2 (DM2) and chronic alcohol intoxication. The most common form of diabetic neuropathy (30-50% of patients with diabetes) is diabetic polyneuropathy (DPN) characterized by intense, severe pain. Distal symmetrical sensory polyneuropathy (SDSP) develops in patients with type 2 diabetes and is marked by an intense neuropathic pain syndrome; it occurs in 20-30% of cases, and its frequency and representativeness increase as the disease progresses. Vitamins B1, B6, B12 enhance neurotropic activity, while the deficiency of each one leads to polyneuropathy. A combination of thiamine, pyridoxine and cyanocobalamin is good for relieving pain and eliminating sensitivity disorders. There is data on the high efficiency and practical value of group B vitamins (Neuromultivit) in the treatment of DPN in patients with type 2 diabetes and alcoholic neuropathy, which is the second most common somatic neuropathy (after diabetic).
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