A Unique Radiation Scheme for the Treatment of High-Grade Non-Metastatic Soft Tissue Sarcoma: The Detroit Medical Center Experience
James Fontanesi,
Michael P. Mott,
Michael J. Kraut,
David R. Lucas,
Peter R. Miller
Affiliations
James Fontanesi
Department of Radiation Oncology, University of Mississippi Medical Center, 2500 North State Street, Jackson 39216, MS, USA
Michael P. Mott
Department of Orthopedic Surgery, Wayne State University School of Medicine, Pathology and Diagnostic Imaging, Detroit 48201, MI, USA
Michael J. Kraut
Department of Medical Oncology, Providence Hospital, Barbara Ann Karmanos Cancer Institute, Detroit 48201, MI, USA
David R. Lucas
Department of Pathology, Wayne State University School of Medicine, Detroit Medical Center, Wayne State University, 4100 John R, Detroit 48201, MI, USA
Peter R. Miller
Department of Radiology, Wayne State University School of Medicine, Detroit Medical Center, Wayne State University, 4100 John R, Detroit 48201, MI, USA
Purpose:This is the initial report on the utilization of combined photon irradiation followed by a neutron boost irradiation for the initial management of patients with high-grade non-metastatic soft tissue sarcoma (STS). We present data on local control, complications, disease-free survival and overall survival in patients at high risk for local relapse.
