A rapid access to aliphatic sulfonyl fluorides

Ruting Xu; Tianxiao Xu; Mingcheng Yang; Tianpeng Cao; Saihu Liao

doi:10.1038/s41467-019-11805-6

Nature Communications (Aug 2019)

A rapid access to aliphatic sulfonyl fluorides

Ruting Xu,
Tianxiao Xu,
Mingcheng Yang,
Tianpeng Cao,
Saihu Liao

Affiliations

Ruting Xu: Key Laboratory for Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University
Tianxiao Xu: Key Laboratory for Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University
Mingcheng Yang: Key Laboratory for Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University
Tianpeng Cao: Key Laboratory for Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University
Saihu Liao: Key Laboratory for Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University

DOI: https://doi.org/10.1038/s41467-019-11805-6
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 7

Abstract

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Sulfonyl fluorides are important probes in chemical biology and molecular pharmacology. Here, the authors report a mild visible light-mediated decarboxylative fluorosulfonylethylation for the synthesis of aliphatic sulfonyl fluorides from a wide range of carboxylic acids, including natural products and drug derivatives.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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