Impact of waist circumference on hospital outcome and coronary angiographic findings of patients with acute ST-segment elevation myocardial infarction

Abstract

Background: Several studies showed that ST-segment elevation myocardial infarction (STEMI) patients with high body mass index (BMI) have better in-hospital outcomes. Aim: This study examined the impact of waist circumference (WC) on the hospital outcome and coronary angiographic extent of STEMI patients. Methods: We evaluated 142 consecutive patients with STEMI. Patients were classified into 2 groups according to WC. Group A (n = 72) had increased WC (WC > 88/102 cm for women/men). Group B (n = 70) had normal WC. A primary composite outcome of in-hospital mortality and cardiovascular complications namely heart failure, cardiogenic shock, serious arrhythmias, re-infarction, post infarction angina, a secondary outcome of in-hospital mortality and coronary angiographic findings were compared between the 2 groups. Results: Group A patients were significantly older, had a significantly higher prevalence of hypertension (HTN), diabetes mellitus (DM) and were significantly less likely to be smokers compared to group B. There was no statistically significant difference in the primary outcome between the 2 groups. WC as a categorical or as a continuous variable did not have any significant influence on the secondary outcome of in-hospital mortality even after adjustment for other predictors of death. Age was the only statistically significant predictor for mortality (p = 0.01). Coronary angiography revealed no statistically significant difference in the number of diseased coronary vessels, number of coronary lesions or Gensini score between the 2 groups. Conclusion: A high WC, had no favorable impact on in-hospital mortality, cardiovascular complications or coronary angiographic extent in STEMI patients.

Keywords

• Obesity
• Waist circumference
• Acute ST segment elevation myocardial infarction
• Gensini score