Regioselective alkali metal reduction of dibenzocyclooctadiene lignan derivatives, demethoxylation followed by dehalogenation

Abstract

Abstract The regioselective demethoxylation and dehalogenation of dihalogenated dibenzocyclooctadiene lignans derivatives were realized in a one-step reaction with excellent yields in the sodium and t-butanol reaction system.

Keywords

• Alkali metal
• Regioselective demethoxylation
• Dehalogenation
• Halogenated dibenzocyclooctadiene lignans
• Aryl halides