Attentional control influence habituation through modulation of connectivity patterns within the prefrontal cortex: Insights from stereo-EEG
Huimin Huang,
Rui Li,
Xiaojun Qiao,
Xiaoran Li,
Ziyue Li,
Siyi Chen,
Yi Yao,
Fengpeng Wang,
Xiaobin Zhang,
Kaomin Lin,
Junsong Zhang
Affiliations
Huimin Huang
Brain Cognition and Computing Lab, National Engineering Research Center for E-learning, Central China Normal University, Wuhan, Hubei, China; Brain Cognition and Intelligent Computing Lab, Department of Artificial Intelligence, School of Informatics, Xiamen University, Xiamen, Fujian, China
Rui Li
Brain Cognition and Computing Lab, National Engineering Research Center for E-learning, Central China Normal University, Wuhan, Hubei, China
Xiaojun Qiao
Brain Cognition and Computing Lab, National Engineering Research Center for E-learning, Central China Normal University, Wuhan, Hubei, China
Xiaoran Li
Brain Cognition and Intelligent Computing Lab, Department of Artificial Intelligence, School of Informatics, Xiamen University, Xiamen, Fujian, China
Ziyue Li
Brain Cognition and Intelligent Computing Lab, Department of Artificial Intelligence, School of Informatics, Xiamen University, Xiamen, Fujian, China
Siyi Chen
Brain Cognition and Intelligent Computing Lab, Department of Artificial Intelligence, School of Informatics, Xiamen University, Xiamen, Fujian, China
Yi Yao
Epilepsy Center, Xiamen Humanity Hospital, Xiamen, Fujian, China
Fengpeng Wang
Epilepsy Center, Xiamen Humanity Hospital, Xiamen, Fujian, China
Xiaobin Zhang
Epilepsy Center, Xiamen Humanity Hospital, Xiamen, Fujian, China
Kaomin Lin
Epilepsy Center, Xiamen Humanity Hospital, Xiamen, Fujian, China
Junsong Zhang
Brain Cognition and Intelligent Computing Lab, Department of Artificial Intelligence, School of Informatics, Xiamen University, Xiamen, Fujian, China; Corresponding author.
Attentional control, guided by top-down processes, enables selective focus on pertinent information, while habituation, influenced by bottom-up factors and prior experiences, shapes cognitive responses by emphasizing stimulus relevance. These two fundamental processes collaborate to regulate cognitive behavior, with the prefrontal cortex and its subregions playing a pivotal role. Nevertheless, the intricate neural mechanisms underlying the interaction between attentional control and habituation are still a subject of ongoing exploration. To our knowledge, there is a dearth of comprehensive studies on the functional connectivity between subsystems within the prefrontal cortex during attentional control processes in both primates and humans. Utilizing stereo-electroencephalogram (SEEG) recordings during the Stroop task, we observed top-down dominance effects and corresponding connectivity patterns among the orbitofrontal cortex (OFC), the middle frontal gyrus (MFG), and the inferior frontal gyrus (IFG) during heightened attentional control. These findings highlighting the involvement of OFC in habituation through top-down attention. Our study unveils unique connectivity profiles, shedding light on the neural interplay between top-down and bottom-up attentional control processes, shaping goal-directed attention.
