Nature Communications (Oct 2017)

Transcription factor Foxo1 is essential for IL-9 induction in T helper cells

  • Sakshi Malik,
  • Srikanth Sadhu,
  • Srikanth Elesela,
  • Ramendra Pati Pandey,
  • Amanpreet Singh Chawla,
  • Deepak Sharma,
  • Lipsa Panda,
  • Deepak Rathore,
  • Balram Ghosh,
  • Vineet Ahuja,
  • Amit Awasthi

DOI
https://doi.org/10.1038/s41467-017-00674-6
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 14

Abstract

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The transcription factor Foxo1 can control regulatory T cell and Th1 function. Here the authors show that Foxo1 is also critical for IL-9 production by Th9 cells and other IL-9-producing cells.