Radiation-induced osteosarcoma of the parotid gland and mandible: A case report and literature review

Fawaz H. Alotaibi; Marwa Hatem; Abdulrahman Hesham; Yousef Alshamrani; David Kim; Jehan Abdulsattar

Oral and Maxillofacial Surgery Cases (Sep 2024)

Radiation-induced osteosarcoma of the parotid gland and mandible: A case report and literature review

Fawaz H. Alotaibi,
Marwa Hatem,
Abdulrahman Hesham,
Yousef Alshamrani,
David Kim,
Jehan Abdulsattar

Affiliations

Fawaz H. Alotaibi: Department of Oral & Maxillofacial Surgery, Head & Neck Oncology, Microvascular Reconstructive Surgery, Louisiana State University Health Science Center, 1501 Kings Highway, Shreveport, LA, 71103, USA; Department of Oral and Maxillofacial Surgery, King Saud University, Riyadh, Saudi Arabia; Corresponding author. Department of Oral & Maxillofacial Surgery, Head & Neck Oncology, Microvascular Reconstructive Surgery, Louisiana State University Health Science Center, 1501 Kings Highway, Shreveport, LA, 71103, USA.
Marwa Hatem: Department of Oral & Maxillofacial Surgery, Head & Neck Oncology, Microvascular Reconstructive Surgery, Louisiana State University Health Science Center, 1501 Kings Highway, Shreveport, LA, 71103, USA
Abdulrahman Hesham: Department of Oral & Maxillofacial Surgery, Head & Neck Oncology, Microvascular Reconstructive Surgery, Louisiana State University Health Science Center, 1501 Kings Highway, Shreveport, LA, 71103, USA
Yousef Alshamrani: Department of Oral & Maxillofacial Surgery, Head & Neck Oncology, Microvascular Reconstructive Surgery, Louisiana State University Health Science Center, 1501 Kings Highway, Shreveport, LA, 71103, USA
David Kim: Department of Oral & Maxillofacial Surgery, Head & Neck Oncology, Microvascular Reconstructive Surgery, Louisiana State University Health Science Center, 1501 Kings Highway, Shreveport, LA, 71103, USA
Jehan Abdulsattar: Department of Pathology and Translational Pathobiology, Louisiana State University Health Science Center, 1501 Kings Highway, Shreveport, LA, 71103, USA

Journal volume & issue: Vol. 10, no. 3
p. 100360

Abstract

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Radiation therapy in treatment of head and neck cancer has contributed to improved survival rate of cancer patients. However, this is accompanied by a potential rise in post radiation complications including radiation induced malignancies and osteoradionecrosis.Radiation Induced Osteosarcoma (RIOS) is rarely reported. In this paper, we report an unusual case of RIOS involving the parotid gland and mandible that was initially misdiagnosed as Osteoradionecrosis (ORN) provide a comprehensive review of the literature.

Published in Oral and Maxillofacial Surgery Cases

ISSN: 2214-5419 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Surgery
Website: https://www.journals.elsevier.com/oral-and-maxillofacial-surgery-cases/

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