Pharmacological Research - Modern Chinese Medicine (Jun 2024)
Exploring the therapeutic potential of Madhuca longifolia in traditional Chinese medicine for the management of kidney stones and various diseases: A review
Abstract
Introduction: Kidney stones (renal calculi), are a common urological problem affecting millions worldwide. Madhuca longifolia (M. longifolia), commonly known as Mahua, has a rich history of medicinal use in various traditional systems, including Traditional Chinese Medicine (TCM). This review aims to explore the therapeutic potential of M. longifolia in the management of kidney stones through the lens of TCM. Methods: Examination of the therapeutic efficacy of M. longifolia in the context of TCM for the treatment of kidney stones was undertaken by performing an exhaustive literature review via internet-based databases, such as PubMed, Scopus, and Google Scholar. Keywords such as ''Madhuca longifolia,'' ''Mahua,'' ''kidney stones,'' ''renal calculi,'' ''Pharmacological activity,'' and ''Traditional Chinese Medicine'' were used to ensure the inclusivity of relevant literature. Studies published between 1972 and 2019 were considered. Inclusion criteria were peer-reviewed articles, systematic reviews, focusing on the health impacts of plant-based diets. Information on the subspecies and cultivars of common names and the scientific names was verified using the Plant List (www.theplantlist.org) database. We retrieved and utilised it for the review of 80 articles. Results: The literature review revealed several studies highlighting the potential therapeutic effects of M. longifolia in the management of kidney stones. The bioactive compounds present in M. longifolia, including flavonoids, phenolic compounds, and saponins, exhibit diuretic, anti-inflammatory, and litholytic properties, which contribute to the dissolution and prevention of kidney stones. Furthermore, Madhuca longifolia demonstrates various pharmacognostic activities, reducing the risk of renal damage associated with kidney stone formation. Discussion: Traditional Chinese Medicine recognizes M. longifolia as a valuable botanical resource for the medical management of kidney calculi. It presents a natural and comprehensive strategy for managing the intricacies associated with kidney stones.
