DBU As A Novel and Highly Efficient Catalyst for The Synthesis of 3,5-Disubstituted-2,6-dicyanoanilines Under Conventional and Microwave Conditions

Abstract

3,5-disubstituted-2,6-dicyanoaniline derivatives have been synthesized via the reaction of aryl methylene- and 1-arylethylidenemalonodinitriles using 1,8-diazabicyclo[5.4.0] undec-7-ene (DBU) as a novel and highly efficient catalyst under conventional as well as microwave conditions. Use of non-hazardous, inexpensive and readily available base catalyst, convenient procedure, short reaction time and improved product yields are some added advantages of the present protocol.

Keywords

• 1,8-diazabicyclo[5.4.0]undec-7-ene (dbu)
• 3,5-disubstituted-2,6-dicyanoanilines
• microwave
• synthesis