Productos inesperados en la transformación química de derivados de la podofilotoxona a través de la reacción de Takai

Abstract

In an unsuccessful attempt to prepare through several routes the 7-deoxo-7-methylene-homothuriferic acid methyl ester from podophyllotoxone, using the Takai reaction, several unexpected products were obtained. In this paper the reaction sequences used and the structural characterization of products obtained are described, as well as an approach on their possible formation mechanisms is briefly commented.

Keywords

• Lignan
• Podophyllotoxone
• Thuriferic acid
• Takai reaction