Molecules (Aug 2011)

Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds

  • Toshiki Nakano,
  • Yusuke Yagi,
  • Motoi Kawatsura,
  • Akio Kaminura,
  • Mizuki Miyahara,
  • Toshiyuki Itoh

DOI
https://doi.org/10.3390/molecules16086747
Journal volume & issue
Vol. 16, no. 8
pp. 6747 – 6757

Abstract

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Optical resolution of 2-methyl-2-nitrobut-3-en-1-ol has been accomplished using a “low-temperature lipase-catalyzed transesterification” carried out at −40 °C.

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