Metastatic brain tumor. Clinical features, diagnosis and treatment

Abstract

The improvement of neuroimaging methods and introduction of the principles of microsurgery and radiosurgery involving the use of the Gamma Knife and CyberKnife systems into clinical practice have significantly changed the treatment outcomes in patients with metastatic brain tumors, thereby allowing to formulate new principles of treating this group of patients. The reported literature review summarizes the available treatment methods for patients with metastatic brain tumors with a focus on overall survival, local control, quality of life, and the capabilities of potential combinations of the existing treatment methods. The paper shows that personalized approaches to treatment of patients with brain metastases are optimal and improve the treatment outcomes.

Keywords

• brain metastases
• radiosurgery
• microsurgery
• whole brain radiotherapy