Armaghane Danesh Bimonthly Journal (Jan 2017)
Comparision effect of adequate intraoperative fluid therapy with dexamethasone on the incidence and severity of nausea and vomiting after general surgery
Abstract
Abstract: Background and aim: Nausea and vomiting are one of the most common and unpleasant side effects of surgery and anesthesia, which causes spasms, aspiration, need more medicine. The researchers express several drugs and methods to reduce transmission of its complications. The aim of this study was to determine the effect of fluid therapy on nausea and vomiting after abdominal surgery. Methods: In this double blind clinical trial study, 120 patients 15-60 years undergoing general participated in Bojnurd. Patients were randomly divided into three groups. Group 1 received adequate intra-operative fluid therapy. Group 2 received pharmacological intervention with dexamethasone 0.1 mg per kg of body weight along with induction of anesthesia- and group 3 - without prophylactic intervention-. The research tools included demographic, visual analogue scale and recorded the number of vomiting. The visual analog scale was used to assess the severity of nausea. In order to assess the severity of vomiting, frequency count was considered as retch or vomit. The scientific validity of content validity was used for data collection. For reliability, the correlation coefficient was used. Based on self-reporting scale, the severity and incidence of nausea and vomiting were evaluated in three stages- post-op, 2 and 6 hours post-op - the data were analyzed with SPSS software. Results: Result showed that the three groups were homogeneous in terms of confounding variables. According one-way ANOVA, the difference between severity and incidence of nausea and vomiting was significantly different among the three groups in the recovery phase. So that based on post hoc test, the difference between the control and fluid therapy with dexamethasone group was significant, and both dexamethasone and fluid therapy had no significant differences in terms of these variables together. Based on the findings the incidence of vomiting was relatively low over time. Conclusion: Regarding the effect of adequate fluid resuscitation on nausea and vomiting after abdominal surgery, this procedure can reduce nausea and vomiting after surgery by low cost and less damage.
