Journal of Cardiothoracic Surgery (Jul 2023)

Xanthoma of rib: a case report and review of the literature

  • Emilia Mottola,
  • Flavia Adotti,
  • Angelina Pernazza,
  • Carlo Della Rocca,
  • Giulia D’Amati,
  • Piergiorgio Nardis,
  • Jacopo Vannucci,
  • Massimiliano Bassi,
  • Federico Venuta,
  • Marco Anile

DOI
https://doi.org/10.1186/s13019-023-02315-0
Journal volume & issue
Vol. 18, no. 1
pp. 1 – 6

Abstract

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Abstract Background Xanthomas are well-circumscribed benign proliferative lesions seen mainly in soft tissues. Usually, they are found in hyperlipidemia and familial hyperlipoproteinemia. Histologically, are characterized by macrophage-like mononuclear cells, multinucleated giant cells and abundant foam cells. The bone involvement, however, is notoriously rare and rib localization is extremely rare. Case presentation A 55-year-old man performed a chest X-ray and a subsequent chest Computed Tomography scan showing a rib lesion that was surgically removed and a diagnosis of rib xanthoma was made. The patient presented an unknown condition of hyperlipidemia. Conclusion Rib xanthoma can be discovered accidentally and can be helpful in identifying an unrecognized condition of hyperlipidemia.

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