Genomic Sequencing Surveillance to Identify Respiratory Syncytial Virus Mutations, Arizona, USA

Abstract

We conducted surveillance of respiratory syncytial virus (RSV) genomic sequences for 100 RSV-A and 27 RSV-B specimens collected during November 2022–April 2023 in Arizona, USA. We identified mutations within prefusion F-protein antigenic sites in both subtypes. Continued genomic surveillance will be critical to ensure RSV vaccine effectiveness.

Keywords

• respiratory syncytial virus
• viruses
• respiratory infections
• RSV
• genomic surveillance
• antigenic sites