Assessment of Microvascular Disease in Heart and Brain by MRI: Application in Heart Failure with Preserved Ejection Fraction and Cerebral Small Vessel Disease

Jonathan Bennett; Maud van Dinther; Paulien Voorter; Walter Backes; Josephine Barnes; Frederick Barkhof; Gabriella Captur; Alun D. Hughes; Carole Sudre; Thomas A. Treibel

doi:10.3390/medicina59091596

Medicina (Sep 2023)

Assessment of Microvascular Disease in Heart and Brain by MRI: Application in Heart Failure with Preserved Ejection Fraction and Cerebral Small Vessel Disease

Jonathan Bennett,
Maud van Dinther,
Paulien Voorter,
Walter Backes,
Josephine Barnes,
Frederick Barkhof,
Gabriella Captur,
Alun D. Hughes,
Carole Sudre,
Thomas A. Treibel

Affiliations

Jonathan Bennett: Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK
Maud van Dinther: Department of Neurology, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands
Paulien Voorter: Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands
Walter Backes: School for Cardiovascular Diseases, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6211 LX Maastricht, The Netherlands
Josephine Barnes: Dementia Research Centre, UCL Queens Square Institute of Neurology, University College London, London WC1E 6BT, UK
Frederick Barkhof: Department of Radiology & Nuclear Medicine, Amsterdam UMC, Vrije University, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
Gabriella Captur: Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK
Alun D. Hughes: Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK
Carole Sudre: Dementia Research Centre, UCL Queens Square Institute of Neurology, University College London, London WC1E 6BT, UK
Thomas A. Treibel: Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK

DOI: https://doi.org/10.3390/medicina59091596
Journal volume & issue: Vol. 59, no. 9
p. 1596

Abstract

Read online

The objective of this review is to investigate the commonalities of microvascular (small vessel) disease in heart failure with preserved ejection fraction (HFpEF) and cerebral small vessel disease (CSVD). Furthermore, the review aims to evaluate the current magnetic resonance imaging (MRI) diagnostic techniques for both conditions. By comparing the two conditions, this review seeks to identify potential opportunities to improve the understanding of both HFpEF and CSVD.

Published in Medicina

ISSN: 1010-660X (Print); 1648-9144 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: https://www.mdpi.com/journal/medicina

About the journal

Abstract

Keywords