Communications Biology (May 2022)
The early-life exposome modulates the effect of polymorphic inversions on DNA methylation
- Natàlia Carreras-Gallo,
- Alejandro Cáceres,
- Laura Balagué-Dobón,
- Carlos Ruiz-Arenas,
- Sandra Andrusaityte,
- Ángel Carracedo,
- Maribel Casas,
- Leda Chatzi,
- Regina Grazuleviciene,
- Kristine Bjerve Gutzkow,
- Johanna Lepeule,
- Léa Maitre,
- Mark Nieuwenhuijsen,
- Remy Slama,
- Nikos Stratakis,
- Cathrine Thomsen,
- Jose Urquiza,
- John Wright,
- Tiffany Yang,
- Geòrgia Escaramís,
- Mariona Bustamante,
- Martine Vrijheid,
- Luis A. Pérez-Jurado,
- Juan R. González
Affiliations
- Natàlia Carreras-Gallo
- Barcelona Institute for Global Health (ISGlobal)
- Alejandro Cáceres
- Barcelona Institute for Global Health (ISGlobal)
- Laura Balagué-Dobón
- Barcelona Institute for Global Health (ISGlobal)
- Carlos Ruiz-Arenas
- Institut Hospital del Mar d’Investigacions Mediques (IMIM)
- Sandra Andrusaityte
- Department of Environmental Science, Vytautas Magnus University
- Ángel Carracedo
- Medicine Genomics Group, Centro de Investigación Biomédica en Red Enfermedades Raras (CIBERER), University of Santiago de Compostela
- Maribel Casas
- Barcelona Institute for Global Health (ISGlobal)
- Leda Chatzi
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Regina Grazuleviciene
- Department of Environmental Science, Vytautas Magnus University
- Kristine Bjerve Gutzkow
- Department of Environmental Health, Norwegian Institute of Public Health
- Johanna Lepeule
- Institut national de la santé et de la recherche médicale (Inserm) and Université Grenoble-Alpes, Institute for Advanced Biosciences (IAB), Team of Environmental Epidemiology applied to Reproduction and Respiratory Health
- Léa Maitre
- Barcelona Institute for Global Health (ISGlobal)
- Mark Nieuwenhuijsen
- Barcelona Institute for Global Health (ISGlobal)
- Remy Slama
- Institut national de la santé et de la recherche médicale (Inserm) and Université Grenoble-Alpes, Institute for Advanced Biosciences (IAB), Team of Environmental Epidemiology applied to Reproduction and Respiratory Health
- Nikos Stratakis
- Barcelona Institute for Global Health (ISGlobal)
- Cathrine Thomsen
- Department of Environmental Health, Norwegian Institute of Public Health
- Jose Urquiza
- Barcelona Institute for Global Health (ISGlobal)
- John Wright
- Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust
- Tiffany Yang
- Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust
- Geòrgia Escaramís
- Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública (CIBERESP)
- Mariona Bustamante
- Barcelona Institute for Global Health (ISGlobal)
- Martine Vrijheid
- Barcelona Institute for Global Health (ISGlobal)
- Luis A. Pérez-Jurado
- Institut Hospital del Mar d’Investigacions Mediques (IMIM)
- Juan R. González
- Barcelona Institute for Global Health (ISGlobal)
- DOI
- https://doi.org/10.1038/s42003-022-03380-2
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 13
Abstract
Analysis of the relationship between presence of common DNA sequence inversions and DNA methylation patterns suggests a role for environmental exposures (such as food intake) in mediating inversion state-specific methylation patterns.
