Clinical study of electrophysiological changes of optic nerves in early period of type 1 diabetes mellitus

Quan-Liang Zhao; Chun-Xiang Zhang; Bao-Fen Jian

doi:10.3980/j.issn.1672-5123.2016.7.28

Guoji Yanke Zazhi (Jul 2016)

Clinical study of electrophysiological changes of optic nerves in early period of type 1 diabetes mellitus

Quan-Liang Zhao,
Chun-Xiang Zhang,
Bao-Fen Jian

Affiliations

Quan-Liang Zhao: Department of Ophthalmology, the Second Affiliated Hospital of Inner Mongolia University for Nationalities, Yakeshi 022150, Inner Mongolia Autonomous Region, China
Chun-Xiang Zhang: Department of Endocrinology, the Second Affiliated Hospital of Inner Mongolia University for Nationalities, Yakeshi 022150, Inner Mongolia Autonomous Region, China
Bao-Fen Jian: Changchun Red-star Hospital, Changchun 130000, Jilin Province, China

DOI: https://doi.org/10.3980/j.issn.1672-5123.2016.7.28
Journal volume & issue: Vol. 16, no. 7
pp. 1316 – 1318

Abstract

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AIM:To investigate the value of pattern visual evoked potential(PVEP)and flash electroretinogram(FERG)in early diagnosis and prevention of diabetic retinopathy(DR), analyzing the correlation of early stage DR with PVEP and FERG.METHODS:Sixty patients, 30 males and 30 females, participated in observation group. Their average age was 19.42±7.78years. The duration of DM was RESULTS:In observation group, P100 amplitude decreased and P100 latency increased, compared to those of control group(PPCONCLUSION: PVEP are sensitive to optic neuron damage; FERG is desirable to detect the lesion of Müller cells and bipolar cells. P100 amplitude by PVEP, b-wave amplitude by FERG may be the most sensitive parameter for DR at early stage.

Published in Guoji Yanke Zazhi

ISSN: 1672-5123 (Print)
Publisher: Press of International Journal of Ophthalmology (IJO PRESS)
Country of publisher: China
LCC subjects: Medicine: Ophthalmology
Website: http://ies.ijo.cn/

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Abstract

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