Cellular Oncology (Jan 2008)

Alterations in AP-1 and AP-1 Regulatory Genes during HPV-Induced Carcinogenesis

  • Jillian de Wilde,
  • Johanna De-Castro Arce,
  • Peter J. F. Snijders,
  • Chris J. L. M. Meijer,
  • Frank Rösl,
  • Renske D. M. Steenbergen

DOI
https://doi.org/10.1155/2008/279656
Journal volume & issue
Vol. 30, no. 1
pp. 77 – 87

Abstract

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Background: Previous studies demonstrated a functional involvement of the AP-1 transcription factor in HPV-induced cervical carcinogenesis. Here, we aimed to obtain further insight in expression alterations of AP-1 family members during HPV-mediated transformation and their relationship to potential regulatory (Notch1, Net) and target (CADM1) genes.