Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Dengjie Yu; Zijun Cai; Daishi Li; Yi Zhang; Miao He; Yuntao Yang; Di Liu; Wenqing Xie; Yusheng Li; Wenfeng Xiao

doi:10.1155/2021/8884283

Stem Cells International (Jan 2021)

Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Dengjie Yu,
Zijun Cai,
Daishi Li,
Yi Zhang,
Miao He,
Yuntao Yang,
Di Liu,
Wenqing Xie,
Yusheng Li,
Wenfeng Xiao

Affiliations

Dengjie Yu: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Zijun Cai: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Daishi Li: Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China
Yi Zhang: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Miao He: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Yuntao Yang: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Di Liu: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Wenqing Xie: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Yusheng Li: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China
Wenfeng Xiao: Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China

DOI: https://doi.org/10.1155/2021/8884283
Journal volume & issue: Vol. 2021

Abstract

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Stem cells have become a hot research topic in the field of regenerative medicine due to their self-renewal and differentiation capabilities. Skeletal muscle tissue is one of the most important tissues in the human body, and it is difficult to recover when severely damaged. However, conventional treatment methods can cause great pain to patients. Stem cell-based tissue engineering can repair skeletal muscle to the greatest extent with little damage. Therefore, the application of stem cells to skeletal muscle regeneration is very promising. In this review, we discuss scaffolds and stem cells for skeletal muscle regeneration and put forward our ideas for future development.

Published in Stem Cells International

ISSN: 1687-966X (Print); 1687-9678 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine
Website: https://onlinelibrary.wiley.com/journal/4162

About the journal