Nature Communications (Feb 2021)

Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila

  • Li Yan McCurdy,
  • Preeti Sareen,
  • Pasha A. Davoudian,
  • Michael N. Nitabach

DOI
https://doi.org/10.1038/s41467-021-21388-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 17

Abstract

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Unexpected omission of aversive outcome is encoded as reward via activation of reward-encoding dopaminergic neurons in animals. The authors identify the Drosophila neural circuit through which reward-encoding dopaminergic neurons are activated when an olfactory cue is no longer paired with punishment.