Case report: Paroxysmal nocturnal hemoglobinuria presenting with hemorrhagic esophageal varices

Runsen Du; Runsen Du; Lihua Zheng; Peng Liu; Yaheng Zhao; Yan Yang; Lei Zhang; Zengren Zhao

doi:10.3389/fmed.2023.1276030

Frontiers in Medicine (Oct 2023)

Case report: Paroxysmal nocturnal hemoglobinuria presenting with hemorrhagic esophageal varices

Runsen Du,
Runsen Du,
Lihua Zheng,
Peng Liu,
Yaheng Zhao,
Yan Yang,
Lei Zhang,
Zengren Zhao

Affiliations

Runsen Du: Department of Gastrointestinal Surgery, The First Hospital of Hebei Medical University, Hebei, China
Runsen Du: Department of Vascular Surgery, The First Hospital of Hebei Medical University, Hebei, China
Lihua Zheng: Department of Vascular Surgery, The First Hospital of Hebei Medical University, Hebei, China
Peng Liu: Department of Vascular Surgery, The First Hospital of Hebei Medical University, Hebei, China
Yaheng Zhao: Department of Vascular Surgery, The First Hospital of Hebei Medical University, Hebei, China
Yan Yang: Department of Vascular Surgery, The First Hospital of Hebei Medical University, Hebei, China
Lei Zhang: Department of Vascular Surgery, The First Hospital of Hebei Medical University, Hebei, China
Zengren Zhao: Department of Gastrointestinal Surgery, The First Hospital of Hebei Medical University, Hebei, China

DOI: https://doi.org/10.3389/fmed.2023.1276030
Journal volume & issue: Vol. 10

Abstract

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We report the case of a female who was cured of hemorrhagic esophageal varices caused by paroxysmal nocturnal hemoglobinuria (PNH) through transjugular intrahepatic portosystemic shunt (TIPS) treatment. PNH complicated by portal vein and visceral veins thrombosis without hepatic veins is extremely rare, and as such, it is easy to incorrectly treat due to lack of awareness. Hemorrhagic esophageal varices due to PNH with PVT have been reported in one case in 1974, and here, we report the second.

Published in Frontiers in Medicine

ISSN: 2296-858X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.frontiersin.org/journals/medicine

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