Regional variation in health is predominantly driven by lifestyle rather than genetics

Carmen Amador; Charley Xia; Réka Nagy; Archie Campbell; David Porteous; Blair H. Smith; Nick Hastie; Veronique Vitart; Caroline Hayward; Pau Navarro; Chris S. Haley

doi:10.1038/s41467-017-00497-5

Nature Communications (Oct 2017)

Regional variation in health is predominantly driven by lifestyle rather than genetics

Carmen Amador,
Charley Xia,
Réka Nagy,
Archie Campbell,
David Porteous,
Blair H. Smith,
Nick Hastie,
Veronique Vitart,
Caroline Hayward,
Pau Navarro,
Chris S. Haley

Affiliations

Carmen Amador: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh
Charley Xia: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh
Réka Nagy: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh
Archie Campbell: Centre for Genomic and Experimental Medicine, Institute of Genetic and Molecular Medicine, University of Edinburgh
David Porteous: Centre for Genomic and Experimental Medicine, Institute of Genetic and Molecular Medicine, University of Edinburgh
Blair H. Smith: Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetic and Experimental Medicine, University of Edinburgh
Nick Hastie: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh
Veronique Vitart: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh
Caroline Hayward: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh
Pau Navarro: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh
Chris S. Haley: MRC Human Genetics Unit, Institute of Genetic and Molecular Medicine, University of Edinburgh

DOI: https://doi.org/10.1038/s41467-017-00497-5
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 7

Abstract

Read online

Health-related traits are known to vary geographically. Here, Amador and colleagues show that regional variation of obesity-related traits in a Scottish population is influenced more by lifestyle differences than it is by genetic differences.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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