Emerging Infectious Diseases (Mar 2009)

Evaluation of Commercially Available Anti–Dengue Virus Immunoglobulin M Tests

  • Elizabeth A. Hunsperger,
  • Sutee Yoksan,
  • Philippe Buchy,
  • Vinh Chau Nguyen,
  • Shamala D. Sekaran,
  • Delia A. Enria,
  • Jose L. Pelegrino,
  • Susana Vázquez,
  • Harvey Artsob,
  • Michael Drebot,
  • Duane J. Gubler,
  • Scott B. Halstead,
  • María G. Guzmán,
  • Harold S. Margolis,
  • Carl-Michael Nathanson,
  • Nidia R. Rizzo Lic,
  • Kovi E. Bessoff,
  • Srisakul Kliks,
  • Rosanna W. Peeling

DOI
https://doi.org/10.3201/eid1503.080923
Journal volume & issue
Vol. 15, no. 3
pp. 436 – 439

Abstract

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Anti–dengue virus immunoglobulin M kits were evaluated. Test sensitivities were 21%–99% and specificities were 77%–98% compared with reference ELISAs. False-positive results were found for patients with malaria or past dengue infections. Three ELISAs showing strong agreement with reference ELISAs will be included in the World Health Organization Bulk Procurement Scheme.

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