Scientific Reports (Aug 2022)

Effects of Thai native chicken breast meat consumption on serum uric acid level, biochemical parameters, and antioxidant activities in rats

  • Prapassorn Potue,
  • Petcharat Chiangsaen,
  • Putcharawipa Maneesai,
  • Juthamas Khamseekaew,
  • Poungrat Pakdeechote,
  • Vibuntita Chankitisakul,
  • Wuttigrai Boonkum,
  • Natthaya Duanghaklang,
  • Monchai Duangjinda

DOI
https://doi.org/10.1038/s41598-022-18484-2
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Abstract This study aimed to evaluate the effect of a high protein diet comprising breast meat from commercial broiler (BR), Thai native (PD), and commercial broiler × Thai native crossbred (KKU-ONE) chicken on serum uric acid, biochemical parameters, and antioxidant activities in rats. Male Sprague–Dawley rats were divided into four groups. The control group received a standard chow diet, and the other three groups were fed a high protein diet (70% standard diet + 30% BR, PD, or KKU-ONE chicken breast) for five weeks. The PD- and KKU-ONE-fed rats had lower plasma total cholesterol and triglyceride levels than the control rats. A decrease in HDL-c was also observed in rats fed a diet containing BR. Liver weight, liver enzyme, plasma ALP, xanthine oxidase activity, serum uric acid, creatinine, superoxide production, and plasma malondialdehyde levels increased in BR-fed rats. The findings of this study might provide evidence to support the use of Thai native and Thai native crossbred chicken breast meat as functional foods.