Macular Optical Coherence Tomography Angiography Parameters in Central Retinal Vein Occlusion and Differentiation of Ischemic and Non-Ischemic Types

Abstract

Aim:To evaluate the macular microvascular parameters in central retinal vein occlusion (CRVO) and to differentiate its ischemic and non-ischemic types.Methods:This study included 32 affected and 32 unaffected eyes of patients with unilateral CRVO and 32 age and sex-matched healthy control eyes. All participants had 6x6 scan pattern macular optical coherence tomography, optical coherence tomography angiography (OCTA) imaging. Vessel density (VD), perfusion density (PD), and foveal avascular zone area measurements of the superficial capillary plexus (SCP) were automatically calculated.Results:There were statistically significant differences among the affected and unaffected eyes of CRVO patients and the control eyes in terms of the mean VD of the central ring and the median PD of the central and inner ring. There was a significant decrease in the mean VD and PD values of the inner and outer ring in the ischemic CRVO types compared to the non-ischemic types.Conclusion:The results of this study showed that VD and PD in SCP were significantly affected CRVO. The alterations were more pronounced in ischemic type of CRVO. OCTA imaging may provide valuable information on early prediction of ischemic and non-ischemic CRVO types.

Keywords

• ischemia
• perfusion
• retinal vein occlusion