Frontiers in Cardiovascular Medicine (Jun 2023)
Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition
- Maja Hanuna,
- Joseph Pattathu,
- Joscha Buech,
- Joscha Buech,
- Christine Kamla,
- Nikolaus Kneidinger,
- Nikolaus Kneidinger,
- Juergen Behr,
- Juergen Behr,
- Katrin Milger,
- Katrin Milger,
- Tobias Veit,
- Tobias Veit,
- Marina Nagel,
- Jan Abicht,
- Robert Dalla-Pozza,
- Marcus Fischer,
- Andre Jakob,
- Matthias Hermann,
- Rene Schramm,
- Laura L. Rosenthal,
- Nikolaus Haas,
- Jürgen Hörer,
- Jürgen Hörer,
- Christian Hagl,
- Christian Hagl,
- Christian Hagl,
- Sebastian G. Michel,
- Sebastian G. Michel,
- Sebastian G. Michel,
- Sebastian G. Michel,
- Sebastian G. Michel
Affiliations
- Maja Hanuna
- Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Joseph Pattathu
- Department of Pediatric Cardiology and Intensive Care, Ludwig Maximilian University Munich, Munich, Germany
- Joscha Buech
- Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Joscha Buech
- Munich Heart Alliance, German Center for Cardiovascular Research (DZHK), Munich, Germany
- Christine Kamla
- Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Nikolaus Kneidinger
- Comprehensive Pneumology Center Munich, German Center for Lung Research (DZL), Munich, Germany
- Nikolaus Kneidinger
- Department of Medicine V, Pulmonology, Ludwig Maximilian University Munich, Munich, Germany
- Juergen Behr
- Comprehensive Pneumology Center Munich, German Center for Lung Research (DZL), Munich, Germany
- Juergen Behr
- Department of Medicine V, Pulmonology, Ludwig Maximilian University Munich, Munich, Germany
- Katrin Milger
- Comprehensive Pneumology Center Munich, German Center for Lung Research (DZL), Munich, Germany
- Katrin Milger
- Department of Medicine V, Pulmonology, Ludwig Maximilian University Munich, Munich, Germany
- Tobias Veit
- Comprehensive Pneumology Center Munich, German Center for Lung Research (DZL), Munich, Germany
- Tobias Veit
- Department of Medicine V, Pulmonology, Ludwig Maximilian University Munich, Munich, Germany
- Marina Nagel
- Department of Pediatric Cardiology and Intensive Care, Ludwig Maximilian University Munich, Munich, Germany
- Jan Abicht
- Department of Anesthesiology, Ludwig Maximilian University Munich, Munich, Germany
- Robert Dalla-Pozza
- Department of Pediatric Cardiology and Intensive Care, Ludwig Maximilian University Munich, Munich, Germany
- Marcus Fischer
- Department of Pediatric Cardiology and Intensive Care, Ludwig Maximilian University Munich, Munich, Germany
- Andre Jakob
- Department of Pediatric Cardiology and Intensive Care, Ludwig Maximilian University Munich, Munich, Germany
- Matthias Hermann
- Department of Pediatric Cardiology and Intensive Care, Ludwig Maximilian University Munich, Munich, Germany
- Rene Schramm
- Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany
- Laura L. Rosenthal
- Division of Congenital and Pediatric Heart Surgery, Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Nikolaus Haas
- Department of Pediatric Cardiology and Intensive Care, Ludwig Maximilian University Munich, Munich, Germany
- Jürgen Hörer
- Division of Congenital and Pediatric Heart Surgery, Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Jürgen Hörer
- Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technical University of Munich, Munich, Germany
- Christian Hagl
- Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Christian Hagl
- Comprehensive Pneumology Center Munich, German Center for Lung Research (DZL), Munich, Germany
- Christian Hagl
- Munich Heart Alliance, German Center for Cardiovascular Research (DZHK), Munich, Germany
- Sebastian G. Michel
- Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Sebastian G. Michel
- Munich Heart Alliance, German Center for Cardiovascular Research (DZHK), Munich, Germany
- Sebastian G. Michel
- Comprehensive Pneumology Center Munich, German Center for Lung Research (DZL), Munich, Germany
- Sebastian G. Michel
- Division of Congenital and Pediatric Heart Surgery, Department of Cardiac Surgery, Ludwig Maximilian University Munich, Munich, Germany
- Sebastian G. Michel
- Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technical University of Munich, Munich, Germany
- DOI
- https://doi.org/10.3389/fcvm.2023.1198204
- Journal volume & issue
-
Vol. 10
Abstract
Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest.
Keywords
- hickmann-catheter
- pulmonary embolism
- chronic thromboembolic pulmonary hypertension
- pulmonary endarterectomy
- parenteral nutrition (PN)
