Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses

• O. Inczefi,
• V. Bacquié,
• M. Olier-Pierre,
• M. Rincel,
• B. Ringot-Destrez,
• S. Ellero-Simatos,
• H. Eutamène,
• C. Bétoulières,
• J. Thomas,
• J. Lainé,
• L. Gros,
• M. Lévêque,
• R. Leonard,
• C. Harkat,
• C. Robbe-Masselot,
• R. Róka,
• M. Mercier-Bonin,
• V. Theodorou,
• M. Darnaudéry,
• J.R. Turner,
• L. Ferrier

Affiliations

O. Inczefi

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France; First Department of Medicine, University of Szeged, Szeged, Hungary

V. Bacquié

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

M. Olier-Pierre

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

M. Rincel

UMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France

B. Ringot-Destrez

Unité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, Villeneuve d’Ascq, France

S. Ellero-Simatos

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

H. Eutamène

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

C. Bétoulières

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

J. Thomas

UMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France

J. Lainé

UMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France

L. Gros

UMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France

M. Lévêque

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

R. Leonard

Unité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, Villeneuve d’Ascq, France

C. Harkat

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

C. Robbe-Masselot

Unité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, Villeneuve d’Ascq, France

R. Róka

First Department of Medicine, University of Szeged, Szeged, Hungary

M. Mercier-Bonin

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

V. Theodorou

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France

M. Darnaudéry

UMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France

J.R. Turner

Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts; Jerrold R. Turner, MD, PhD, Harvard Medical School, Department of Pathology, 77 Avenue Louis Pasteur, NRB 730, Boston, MA 02115.

L. Ferrier

UMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France; Address correspondence to: Laurent Ferrier, PhD, INRAE, UMR 1331 ToxAlim, 180 chemin de Tournefeuille, 31027 Toulouse, France. fax: +33 (0)5 61 28 52 44.