Brazilian Journal of Infectious Diseases ()

Bilateral afrenal nodules due to histoplasmosis in an elderly

  • Flávio Pedreira de Freitas de Carvalho,
  • José Antônio Esper Curiati,
  • Thaís Mauad,
  • Milena Mendes Incerti,
  • Wilson Jacob Filho

DOI
https://doi.org/10.1590/S1413-86702007000100033
Journal volume & issue
Vol. 11, no. 1
pp. 160 – 162

Abstract

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We report a case history of an 84-year-old elderly male patient that presented with a clinical picture suggestive of adrenal failure and bilateral adrenal nodules detected by abdominal computed tomography. A fine needle-guided biopsy was inconclusive for achieving a final diagnosis. The patient died due to septic shock and the autopsy disclosed histoplasmosis with extensive bilateral necrosis of the adrenal glands. Although the adrenal involvement in chronic disseminated histoplasmosis has been described, there have been few reports of the infection being associated with adrenal insufficiency.

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