Comprehensive Structure–Activity Profiling of Micheliolide and its Targeted Proteome in Leukemia Cells via Probe-Guided Late-Stage C–H Functionalization

• Hanan Alwaseem,
• Simone Giovani,
• Michele Crotti,
• Kevin Welle,
• Craig T. Jordan,
• Sina Ghaemmaghami,
• Rudi Fasan

Affiliations

Hanan Alwaseem

Department of Chemistry, University of Rochester, Rochester, New York, United States

Simone Giovani

Department of Chemistry, University of Rochester, Rochester, New York, United States

Michele Crotti

Department of Chemistry, University of Rochester, Rochester, New York, United States

Kevin Welle

Mass Spectrometry Resource Laboratory, University of Rochester Medical School, Rochester, New York, United States

Craig T. Jordan

Department of Hematology, School of Medicine, University of Colorado, Aurora, Colorado, United States

Sina Ghaemmaghami

Mass Spectrometry Resource Laboratory, University of Rochester Medical School, Rochester, New York, United States

Rudi Fasan

Department of Chemistry, University of Rochester, Rochester, New York, United States