Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection

Aurélie Deroubaix; Aurélie Deroubaix; Anna Kramvis

doi:10.3389/fcimb.2022.794264

Frontiers in Cellular and Infection Microbiology (Jul 2022)

Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection

Aurélie Deroubaix,
Aurélie Deroubaix,
Anna Kramvis

Affiliations

Aurélie Deroubaix: Hepatitis Virus Diversity Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Aurélie Deroubaix: Life Sciences Imaging Facility, University of the Witwatersrand, Johannesburg, South Africa
Anna Kramvis: Hepatitis Virus Diversity Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

DOI: https://doi.org/10.3389/fcimb.2022.794264
Journal volume & issue: Vol. 12

Abstract

Read online

The world has seen the emergence of a new virus in 2019, SARS-CoV-2, causing the COVID-19 pandemic and millions of deaths worldwide. Microscopy can be much more informative than conventional detection methods such as RT-PCR. This review aims to present the up-to-date microscopy observations in patients, the in vitro studies of the virus and viral proteins and their interaction with their host, discuss the microscopy techniques for detection and study of SARS-CoV-2, and summarize the reagents used for SARS-CoV-2 detection. From basic fluorescence microscopy to high resolution techniques and combined technologies, this article shows the power and the potential of microscopy techniques, especially in the field of virology.

Published in Frontiers in Cellular and Infection Microbiology

ISSN: 2235-2988 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.frontiersin.org/Cellular-and-Infection-Microbiology

About the journal

Abstract

Keywords