Revolving Door of Histologic Transformation—Tumor Heterogeneity Complicating the Management of EGFR-Mutated Lung Adenocarcinoma: A Case of Jekyll and Hyde

• Michael Wysota, MD,
• Saeed Asiry, MD,
• Yitzhak Goldstein, MD,
• Lecia V. Sequist, MD,
• Samer Khader, MD,
• Balazs Halmos, MD

Affiliations

Michael Wysota, MD

Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Pathology Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York

Saeed Asiry, MD

Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Pathology Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York

Yitzhak Goldstein, MD

Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Pathology Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York

Lecia V. Sequist, MD

Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts

Samer Khader, MD

Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Pathology Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York

Balazs Halmos, MD

Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Pathology Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York; Corresponding author. Address for correspondence: Balazs Halmos, MD, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, 1695 Eastchester Rd., Bronx, NY 10461.