Chemical Constituents from Clematis delavayi var. spinescens

Abstract

A new coumarin, 7-hydroxy-4,6-dimethoxy-5-methylcoumarin (1), was isolated from the aerial parts of Clematis delavayi var. spinescens together with 17 known compounds. Their structures were identified by extensive spectral analysis, especially 2D NMR techniques. Antiangiogenic effects of all compounds were evaluated using a zebrafish model.

Keywords

• coumarin
• Clematis delavayi var. spinescens
• NMR
• antiangiogenic effects