Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection

Nicole M. Davis; Michelle M. Lissner; Crystal L. Richards; Victoria Chevée; Avni S. Gupta; Frank C. Gherardini; David S. Schneider

doi:10.1128/mBio.02424-21

mBio (Oct 2021)

Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection

Nicole M. Davis,
Michelle M. Lissner,
Crystal L. Richards,
Victoria Chevée,
Avni S. Gupta,
Frank C. Gherardini,
David S. Schneider

Affiliations

Nicole M. Davis: ORCiD; Department of Microbiology and Immunology, Stanford University, Stanford, California, USA
Michelle M. Lissner: Department of Microbiology and Immunology, Stanford University, Stanford, California, USA
Crystal L. Richards: Laboratory of Bacteriology, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratories, Hamilton, Montana, USA
Victoria Chevée: Department of Microbiology and Immunology, Stanford University, Stanford, California, USA
Avni S. Gupta: Department of Microbiology and Immunology, Stanford University, Stanford, California, USA
Frank C. Gherardini: Laboratory of Bacteriology, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratories, Hamilton, Montana, USA
David S. Schneider: ORCiD; Department of Microbiology and Immunology, Stanford University, Stanford, California, USA

DOI: https://doi.org/10.1128/mBio.02424-21
Journal volume & issue: Vol. 12, no. 5

Abstract

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Malaria is a severe and sometimes fatal infectious disease endemic to tropical and subtropical regions. Effective vaccines against malaria-causing Plasmodium

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

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