Evaluation Of Treatment Modalities For Vitiligo At Sites Difficult To Treat-A Preliminary Report

Abstract

The treatment of vitiligo involving the mucosae, acral areas, palms and soles is an arduous challenge. No definite treatment guideline exists for these patients. The preliminary results of evaluation of four different treatment regimens in these patients are presented. Forty patients were alternatively assigned to 4 regimens comprising of PUVASOL: PUVASOL with levamisole: topical corticosteroids and topical corticosteroids with levamisole. All the four regimens gave comparable results. PUVASOL and topical corticosteroids used alone or in combination with levamisole are all equally effective in treating the so called “difficult to treat or resistant” sites in vitiligo with cosmetically acceptable results (25.50% pigmentation) after 6 months of therapy.