Nature Communications (Oct 2020)

A fast impedance-based antimicrobial susceptibility test

  • Daniel C. Spencer,
  • Teagan F. Paton,
  • Kieran T. Mulroney,
  • Timothy J. J. Inglis,
  • J. Mark Sutton,
  • Hywel Morgan

DOI
https://doi.org/10.1038/s41467-020-18902-x
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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There is an urgent need to develop simple and fast antimicrobial susceptibility tests. Here, Spencer et al. describe a label-free test that can deliver results within an hour, consisting of a 30-min antibiotic treatment followed by single-cell analysis of phenotypic responses with microfluidic impedance cytometry.