A fast impedance-based antimicrobial susceptibility test

Daniel C. Spencer; Teagan F. Paton; Kieran T. Mulroney; Timothy J. J. Inglis; J. Mark Sutton; Hywel Morgan

doi:10.1038/s41467-020-18902-x

Nature Communications (Oct 2020)

A fast impedance-based antimicrobial susceptibility test

Daniel C. Spencer,
Teagan F. Paton,
Kieran T. Mulroney,
Timothy J. J. Inglis,
J. Mark Sutton,
Hywel Morgan

Affiliations

Daniel C. Spencer: Department of Electronics and Computer Science, and Institute for Life Science, University of Southampton
Teagan F. Paton: Department of Microbiology, PathWest Laboratory Medicine
Kieran T. Mulroney: Faculty of Health and Medical Sciences, University of Western Australia
Timothy J. J. Inglis: Department of Microbiology, PathWest Laboratory Medicine
J. Mark Sutton: Public Health England, National Infection Service
Hywel Morgan: Department of Electronics and Computer Science, and Institute for Life Science, University of Southampton

DOI: https://doi.org/10.1038/s41467-020-18902-x
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 11

Abstract

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There is an urgent need to develop simple and fast antimicrobial susceptibility tests. Here, Spencer et al. describe a label-free test that can deliver results within an hour, consisting of a 30-min antibiotic treatment followed by single-cell analysis of phenotypic responses with microfluidic impedance cytometry.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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