Non-clostridial Gas-forming Infection in Diabetes：Clinical Analysis of Two Cases

Abstract

Non-clostridial organism can produce pneumoderma by breaking down sugar and other substrates in necrotic tissues, and non-clostridial gas-forming infection is usually seen in diabetic patients with poor glycemic control. The differential diagnosis between clostridial and non-clostridial gas-forming infection relies on etiological examination results, but the key to successful treatment is timely empiric broad-spectrum antibiotic treatment and emergency surgical debridement in the absence of a definitive etiologic diagnosis. This paper reported two cases of non-clostridial gas-forming infection in diabetes, and reviewed relevant literature, aiming to improve clinicians' understanding of this disease.

Keywords

• |diabetes mellitus, type 2|infection|gas-forming infection|clostridial|diagnosis|therapy