Nature Communications (Jan 2019)
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
- The IMEx Consortium Curators,
- N. del-Toro,
- M. Duesbury,
- M. Koch,
- L. Perfetto,
- A. Shrivastava,
- D. Ochoa,
- O. Wagih,
- J. Piñero,
- M. Kotlyar,
- C. Pastrello,
- P. Beltrao,
- L. I. Furlong,
- I. Jurisica,
- H. Hermjakob,
- S. Orchard,
- P. Porras
Affiliations
- The IMEx Consortium Curators
- N. del-Toro
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- M. Duesbury
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- M. Koch
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- L. Perfetto
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- A. Shrivastava
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- D. Ochoa
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- O. Wagih
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- J. Piñero
- Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences (DCEXS), Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra (UPF)
- M. Kotlyar
- Krembil Research Institute, Data Science Discovery Centre for Chronic Diseases
- C. Pastrello
- Krembil Research Institute, Data Science Discovery Centre for Chronic Diseases
- P. Beltrao
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- L. I. Furlong
- Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences (DCEXS), Hospital del Mar Medical Research Institute (IMIM), Universitat Pompeu Fabra (UPF)
- I. Jurisica
- Krembil Research Institute, Data Science Discovery Centre for Chronic Diseases
- H. Hermjakob
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- S. Orchard
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- P. Porras
- European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
- DOI
- https://doi.org/10.1038/s41467-018-07709-6
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 14
Abstract
Genetic variants might exert their functional effects via influencing molecular interaction. Here, the authors present a resource featuring almost 28,000 annotations describing the effect of small sequence changes on physical protein interactions, curated by IMEx Consortium curators.
