Stem Cell Research (May 2017)

Generation of human induced pluripotent stem cell lines from human dermal fibroblasts using a non-integration system

  • Kyung-Ok Uhm,
  • So-Jung Kim,
  • Eun Hee Jo,
  • Gue Youn Go,
  • Hye Young Choi,
  • Young Sam Im,
  • Hye-Yeong Ha,
  • Jung-Hyun Kim,
  • Soo Kyung Koo

DOI
https://doi.org/10.1016/j.scr.2017.03.009
Journal volume & issue
Vol. 21, no. C
pp. 13 – 15

Abstract

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We generated human induced pluripotent stem cells (hiPSCs) from dermal fibroblasts using a Sendai virus (SeV)-based gene delivery method. The generated hiPSC line, KSCBi002-A, has a normal karyotype (46,XY). The pluripotency and differentiation capacity were characterized by comparison with those of a human embryonic stem cell line. This cell line is registered and available from the National Stem Cell Bank, Korea National Institute of Health.