Microorganisms (Mar 2024)

Microbial Symphony: Navigating the Intricacies of the Human Oral Microbiome and Its Impact on Health

  • Rahul Bhandary,
  • Geethu Venugopalan,
  • Amitha Ramesh,
  • Guilia Margherita Tartaglia,
  • Ishita Singhal,
  • Shahnawaz Khijmatgar

DOI
https://doi.org/10.3390/microorganisms12030571
Journal volume & issue
Vol. 12, no. 3
p. 571

Abstract

Read online

This comprehensive review delves into the forefront of research on the human oral microbiome, exploring recent advancements that span microbial colonization, state-of-the-art detection methodologies, and the complex interplay involved in disease progression. Through an exhaustive analysis of the contemporary literature, we illuminate the dynamic orchestration of microbial communities within the oral cavity, underscoring their pivotal role in health and disease. Cutting-edge detection techniques, including metagenomics and high-throughput sequencing, are discussed regarding their transformative impact on understanding the intricacies of oral microbial ecosystems. As we stand on the cusp of a new decade, this review anticipates a paradigm shift in the field, emphasizing the potential for rapid identification and targeted management of detrimental oral microorganisms. Insights gained from this exploration not only contribute to our fundamental understanding of the oral microbiome but also hold promise for the development of innovative therapeutic strategies to maintain oral health. This article aims to serve as a valuable resource for researchers, clinicians, and public health professionals engaged in unraveling the mysteries of the microbial symphony within the human oral cavity.

Keywords