Incorporating automation in a cytogenetics laboratory: three practitioners’ perspectives on benefits and limitations

Cecelia Miller; Jennie Thurston; Ninette Cohen

doi:10.1186/s13039-025-00716-5

Molecular Cytogenetics (Jun 2025)

Incorporating automation in a cytogenetics laboratory: three practitioners’ perspectives on benefits and limitations

Cecelia Miller,
Jennie Thurston,
Ninette Cohen

Affiliations

Cecelia Miller: Department of Pathology, College of Medicine, The Ohio State University Wexner Medical Center
Jennie Thurston: Cytogenetics and Molecular Pathology, Atrium Health and CPG Pathology
Ninette Cohen: Department of Pathology and Laboratory Medicine, Division of Cytogenetics and Molecular Pathology, North Shore University Hospital and Long Island Jewish Medical Center, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health

DOI: https://doi.org/10.1186/s13039-025-00716-5
Journal volume & issue: Vol. 18, no. 1
pp. 1 – 8

Abstract

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Abstract Automation has been developed and continues to be refined for cytogenetics, including advances in the processing of samples, in analysis of conventional chromosome and fluorescence in situ hybridization (FISH) testing, and with artificial intelligence. Here we provide an overview of the various types of automation available to the cytogenetics laboratory and discuss possible benefits and limitations you may encounter based upon our collective experiences.

Published in Molecular Cytogenetics

ISSN: 1755-8166 (Online)
Publisher: BMC
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Genetics
Website: https://molecularcytogenetics.biomedcentral.com/

About the journal

Abstract

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