Acta Biomedica Scientifica (Apr 2015)
Use of non-steroid anti-inflammatory preparations for prevention of acute pancreatitis after endoscopic retrograde cholangiopancreatography (literature review)
Abstract
Non-steroid anti-inflammatory preparations (NSAlDs) - a unique class of the medical products possessing analgesic, anti-inflammatory and febrifugal effect. NSAlDs are widely used in various branches of medicine, especially at a pathology of the oporno-impellent device for knocking over of a pain after traumas, and also for symptomatic therapy of acute and chronic rheumatic diseases. Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most important methods for diagnosis of diseases of the pancreatobiliary zone. ln addition to visualizing intraductal changes, this technique allows a wide range of surgical procedures, such as papillosfinkterotomiya, removal of stones, stenting and more. Unfortunately, during ERCP, serious complications may arise, primarily acute pancreatitis. To prevent the development of this pathology are offered a variety of technical and pharmacological approaches, but not all of them have proven effective in clinical trials. One of the most successful means for the prevention of post-ERCP acute pancreatitis was the use of nonsteroidal anti-inflammatory drugs. Appointment NSAlDs at carrying out ERCP - in an hour to - or is direct after procedure, essentially improves its shipping. First of all it is a question of reduction of number and reduction of weight of ERCP - associated acute pancreatitis potentially menacing to life of complication. Though in clinical researches it has not been shown authentic decrease mortality from the given pathology, nevertheless, it is necessary to think that active preventive maintenance will allow to rescue patients from the destruction caused heavy iatrogenic by a pancreatitis. This review is devoted to an analysis of published data on the subject.
