Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in 
rabbits: a positive cross talk between bradykinin,
 nitric oxide and prostaglandin E2

Suzana B. V. Mello; Maria Luiza Guzzo; Luiz Filipe Santiago Lisboa; Sandra H. P. Farsky

doi:10.1080/09629350210306

Mediators of Inflammation (Jan 2002)

Pharmacological characterisation of arthritis induced by Bothrops jararaca venom in rabbits: a positive cross talk between bradykinin, nitric oxide and prostaglandin E2

Suzana B. V. Mello,
Maria Luiza Guzzo,
Luiz Filipe Santiago Lisboa,
Sandra H. P. Farsky

Affiliations

Suzana B. V. Mello: Rheumatology Division, Department of Internal Medicine, School of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, São Paulo, SP 0124–6903, Brazil
Maria Luiza Guzzo: Rheumatology Division, Department of Internal Medicine, School of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, São Paulo, SP 0124–6903, Brazil
Luiz Filipe Santiago Lisboa: Rheumatology Division, Department of Internal Medicine, School of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, São Paulo, SP 0124–6903, Brazil
Sandra H. P. Farsky: Laboratory of Imunochemistry, Instituto Butantan, Av. Vital Brazil 1500, São Paulo, SP 05503–900, Brazil

DOI: https://doi.org/10.1080/09629350210306
Journal volume & issue: Vol. 11, no. 1
pp. 13 – 16

Abstract

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Background: Our previous results showed that nitric oxide (NO) and bradykinin (BK) mediate the arthritis induced by Bothrops jararaca venom (BjV) in rabbits. In this study, we investigated the contribution of each receptor of BK as well as the inter-relationship between NO and eicosanoids in BjV-induced arthritis.

Published in Mediators of Inflammation

ISSN: 0962-9351 (Print); 1466-1861 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Pathology
Website: https://onlinelibrary.wiley.com/journal/4792

About the journal